METTL3 antibody [N2C2], Internal
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||64 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||methyltransferase like 3|
|Product Description||Rabbit polyclonal antibody to METTL3 (methyltransferase like 3)|
|Background||This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq]|
|Synonyms||IME4 antibody, M6A antibody, MGC4336 antibody, MT-A70 antibody, Spo8 antibody, METTL3 antibody, mRNA m(6)A methyltransferase antibody, methyltransferase-like protein 3 antibody, adoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase antibody, N6-adenosine-methyltransferase 70 kDa subunit antibody, methyltransferase like 3 antibody|
|Cellular Localization||Nucleus speckle|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human METTL3. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Zebrafish, Xenopus laevis, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (98%), Rat (98%), Zebrafish (80%), Xenopus laevis (84%), Chimpanzee (100%), Bovine (99%)|