|Full Name||mitofusin 2|
|Product Description||Rabbit Polyclonal antibody to MFN2 (mitofusin 2)|
|Background||This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq]|
|Synonyms||CMT2A antibody, CMT2A2 antibody, CPRP1 antibody, HSG antibody, KIAA0214 antibody, MARF antibody, MFN2 antibody, hyperplasia suppressor antibody, transmembrane GTPase MFN2 antibody, mitofusin-2 antibody, mitochondrial assembly regulatory factor antibody, mitofusin 2 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the N-terminus region of human MFN2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Xenopus Tropicalis, Dog, Bovine|
|Predict Reactivity Note||Rat (96%), Zebrafish (83%), Xenopus laevis (82%), Xenopus Tropicalis (83%), Dog (98%), Bovine (97%)|