|Full Name||mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase|
|Product Description||Rabbit polyclonal antibody to MGAT2 (mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase)|
|Background||The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcript variants with a spliced 5' UTR may exist, but their biological validity has not been determined. [provided by RefSeq]|
|Synonyms||CDG2A antibody, CDGS2 antibody, GLCNACTII antibody, GNT-II antibody, GNT2 antibody, MGAT2 antibody, "Beta-1,2-N-acetylglucosaminyltransferase II antibody", glcNAc-T II antibody, "alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase antibody", N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II antibody, mannoside acetylglucosaminyltransferase 2 antibody, "UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II antibody", "mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase antibody"|
|Cellular Localization||Golgi apparatus membrane; Single-pass type II membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MGAT2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Chimpanzee|
|Predict Reactivity Note||Mouse (84%), Rat (84%), Pig (89%), Chimpanzee (98%)|