|Full Name||mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A|
|Product Description||Rabbit Polyclonal antibody to MGAT4A (mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A)|
|Background||This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation. [provided by RefSeq]|
|Synonyms||GNT-IV antibody, GNT-IVA antibody, MGAT4A antibody, N-acetylglucosaminyltransferase IVa antibody, "UDP-GlcNAc:a-1,3-D-mannoside b-1,4-acetylglucosaminyltransferase IV antibody", "mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isoenzyme A antibody", "UDP-N-acetylglucosamine:alpha1,3-d-mannoside beta1,4-N-acetylglucosaminyltransferase antibody", N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVa antibody, "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A antibody", "UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVa antibody", "alpha-1,3-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase antibody", glcNAc-T IVa antibody, "mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A antibody"|
|Cellular Localization||Alpha-1 , 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A: Golgi apparatus membrane; Single-pass type II membrane protein , 3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A soluble form: Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human MGAT4A. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Chicken, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (94%), Rat (95%), Pig (97%), Chicken (90%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (97%)|