|Full Name||microsomal glutathione S-transferase 1|
|Product Description||Rabbit Polyclonal antibody to MGST1 (microsomal glutathione S-transferase 1)|
|Background||The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Four transcript variants of this gene encode one protein isoform. [provided by RefSeq]|
|Synonyms||MGST Antibody , GST12 Antibody , microsomal glutathione S-transferase 1 Antibody , MGST-I Antibody|
|Cellular Localization||Microsome (By similarity) , Mitochondrion outer membrane; Peripheral membrane protein (By similarity) , Endoplasmic reticulum |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MGST1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Chimpanzee, Bovine|
|Predict Reactivity Note||Pig (89%), Chimpanzee (99%), Bovine (87%)|