|Full Name||microphthalmia-associated transcription factor|
|Product Description||Rabbit Polyclonal antibody to MITF (microphthalmia-associated transcription factor)|
|Background||This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]|
|Synonyms||MI antibody, WS2 antibody, WS2A antibody, bHLHe32 antibody, MITF antibody, microphthalmia-associated transcription factor antibody, class E basic helix-loop-helix protein 32 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MITF. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Dog, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (96%), Dog (99%), Pig (99%), Chicken (93%), Rhesus Monkey (100%), Bovine (99%)|