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1 .GTX50464 MEK3 antibody

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MEK3 antibody


  • Host / ClonalityRabbit Polyclonal
  • ApplicationsICC/IF, IHC-P, WB
  • Species reactivityHuman, Mouse, Rat
Cat No: GTX50464
Package Price Qty
100 μlUSD 319.00
Add to cart
 
  • Anti-MEK3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX50464
  • Anti-MEK3 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX50464
  • Anti-MEK3 antibody used in Western Blot (WB). GTX50464
  • Anti-MEK3 antibody used in Western Blot (WB). GTX50464
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  • Datasheet

  • Application Information: MEK3 antibody

Catalog Number GTX50464
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Product Name MEK3 antibody
See all MEK3 products
ApplicationsICC/IF, IHC-P, WB
Application NoteSuggested starting dilutions are as follows. WB: 1:500~1:1000, IHC-P: 1:50~1:100, ICC/IF: 1:100~1:200. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Predicted Target Size40 (note)
Form SuppliedLiquid
Concentration1 mg/ml (Please refer to the vial label for the specific concentration)
PurificationAntibodies were purified by affinity-chromatography using epitope-specific peptide.

  • Specifications: MEK3 antibody

Full Namemitogen-activated protein kinase kinase 3
BackgroundMEK3 belongs to MAPKK family. This kinase is activated by mitogenic and environmental stress, and participates in the MAPK-mediated signaling cascade. It phosphorylates and thus activates p38. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of Ras oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of p38, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis.
SynonymsMAPKK3, MEK3, MKK3, PRKMK3, MAP2K3, MAPK/ERK kinase 3, MEK 3, SAPK kinase 2, MAP kinase kinase 3, MAPKK 3, dual specificity mitogen-activated protein kinase kinase 3, stress-activated protein kinase kinase 2, mitogen-activated protein kinase kinase 3
HostRabbit
ClonalityPolyclonal
ImmunogenPeptide sequence around aa.187~191 (V-D-S-V-A) derived from Human MEK3.
Antigen SpeciesHuman
Species ReactivityHuman, Mouse, Rat
ConjugationUnconjugated

  • Storage Conditions: MEK3 antibody

Storage Buffersaline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage InstructionKeep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
MEK3 antibody validated data
  • Anti-MEK3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX50464
    • GTX50464 ICC/IF Image
      Immunofluorescence staining of methanol-fixed Hela cells using MKK3 Antibody (GTX50464).
      Top
  • Anti-MEK3 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX50464
    • GTX50464 IHC-P Image
      Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MKK3 Antibody (GTX50464) (left) or the same antibody preincubated with blocking peptide (right).
      Top
  • Anti-MEK3 antibody used in Western Blot (WB). GTX50464
    • GTX50464 WB Image
      Western blot analysis of extracts from MDA cells using MKK3 Antibody (GTX50464).
      Top
  • Anti-MEK3 antibody used in Western Blot (WB). GTX50464
    • GTX50464 WB Image
      Western blot analysis of extracts from MDA cells using MKK3(Ab-189) Antibody GTX50464.
      Top
  • Anti-MEK3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX50464
    • GTX50464 ICC/IF Image
      Immunofluorescence staining of methanol-fixed Hela cells using MKK3 Antibody (GTX50464).
      Top
  • Anti-MEK3 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX50464
    • GTX50464 IHC-P Image
      Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MKK3 Antibody (GTX50464) (left) or the same antibody preincubated with blocking peptide (right).
      Top
  • Anti-MEK3 antibody used in Western Blot (WB). GTX50464
    • GTX50464 WB Image
      Western blot analysis of extracts from MDA cells using MKK3 Antibody (GTX50464).
      Top
  • Anti-MEK3 antibody used in Western Blot (WB). GTX50464
    • GTX50464 WB Image
      Western blot analysis of extracts from MDA cells using MKK3(Ab-189) Antibody GTX50464.
      Top
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