|Full Name||mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)|
|Product Description||Rabbit Polyclonal antibody to MLH1 (mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli))|
|Background||This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined. [provided by RefSeq]|
|Synonyms||COCA2 antibody, FCC2 antibody, HNPCC antibody, HNPCC2 antibody, MGC5172 antibody, hMLH1 antibody, MLH1 antibody, DNA mismatch repair protein Mlh1 antibody, mutL protein homolog 1 antibody, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MLH1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Pig, Bovine|
|Predict Reactivity Note||Mouse (85%), Rat (83%), Pig (91%), Bovine (90%)|