MMACHC antibody [N1C2]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||32 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Raji , mouse brain|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria|
|Product Description||Rabbit Polyclonal antibody to MMACHC (methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria)|
|Background||The exact function of the protein encoded by this gene is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC. [provided by RefSeq]|
|Synonyms||DKFZp564I122 antibody, FLJ25671 antibody, RP11-291L19.3 antibody, cblC antibody, MMACHC antibody, methylmalonic aciduria and homocystinuria type C protein antibody, "methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MMACHC. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (85%), Pig (91%), Rhesus Monkey (96%), Bovine (90%)|