|Full Name||matrix metallopeptidase 1 (interstitial collagenase)|
|Product Description||Rabbit Polyclonal antibody to MMP1 (matrix metallopeptidase 1 (interstitial collagenase))|
|Background||Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq]|
|Synonyms||CLG antibody, CLGN antibody, MMP1 antibody, matrix metalloproteinase 1 antibody, fibroblast collagenase antibody, interstitial collagenase antibody, matrix metalloprotease 1 antibody, matrix metallopeptidase 1 (interstitial collagenase) antibody|
|Cellular Localization||Secreted , extracellular space , extracellular matrix |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MMP1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Rabbit, Bovine|
|Predict Reactivity Note||Pig (91%), Rabbit (89%), Bovine (86%)|