|Full Name||matrix metallopeptidase 13|
|Product Description||Rabbit polyclonal antibody to MMP-13|
|Background||The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen type I, II, III. |
|Synonyms||MMP13, Matrix metalloproteinase13, Collagenase 3, CLG3, Collagenase3, Matrix metalloproteinase 13|
|Specificity||This antibody is specific for MMP-13.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Bovine, Horse, Rat|
|Predict Reactivity Note||Rat (100%), Horse (98%), Bovine (98%)|