|Full Name||matrix metallopeptidase 16 (membrane-inserted)|
|Product Description||Rabbit Polyclonal antibody to MMP16 (matrix metallopeptidase 16 (membrane-inserted))|
|Background||Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene produces at least two transcripts, one which encodes a membrane-bound form and another a soluble form of the protein. Both forms of the protein activate MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. [provided by RefSeq]|
|Synonyms||C8orf57 antibody, DKFZp761D112 antibody, MMP-X2 antibody, MT-MMP2 antibody, MT-MMP3 antibody, MT3-MMP antibody, MMP16 antibody, Putative transmembrane protein C8orf57 antibody, matrix metalloproteinase-16 antibody, membrane-type-3 matrix metalloproteinase antibody, MMP-16 antibody, MT-MMP 3 antibody, MT3MMP antibody, MTMMP3 antibody, membrane-type matrix metalloproteinase 3 antibody, matrix metallopeptidase 16 (membrane-inserted) antibody|
|Cellular Localization||Isoform Long: Cell membrane; Single-pass type I membrane protein; Extracellular side (Potential) , Isoform Short: Secreted , extracellular space , extracellular matrix , Cell surface |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MMP16. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Japanese medaka, Xenopus laevis, Chicken, Bovine|
|Predict Reactivity Note||Japanese medaka (83%), Xenopus laevis (92%), Chicken (98%), Bovine (98%)|