|Full Name||matrix metallopeptidase 17 (membrane-inserted)|
|Product Description||Rabbit Polyclonal antibody to MMP17 (matrix metallopeptidase 17 (membrane-inserted))|
|Background||Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage. [provided by RefSeq]|
|Synonyms||MT4-MMP antibody, MMP17 antibody, MMP-17 antibody, MT4MMP antibody, matrix metalloproteinase 17 (membrane-inserted) antibody, membrane-type matrix metalloproteinase 4 antibody, membrane-type-4 matrix metalloproteinase antibody, matrix metalloproteinase-17 antibody, MTMMP4 antibody, MT-MMP 4 antibody, matrix metallopeptidase 17 (membrane-inserted) antibody|
|Cellular Localization||Isoform Long: Cell membrane; Lipid-anchor , GPI-anchor; Extracellular side , Secreted , extracellular space , extracellular matrix |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MMP17. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (93%), Rat (93%)|