|Full Name||matrix metallopeptidase 7 (matrilysin, uterine)|
|Product Description||Rabbit polyclonal antibody to MMP7 (matrix metallopeptidase 7 (matrilysin, uterine))|
|Background||Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq]|
|Synonyms||MMP-7 antibody, MPSL1 antibody, PUMP-1 antibody, MMP7 antibody, uterine matrilysin antibody, "matrix metalloproteinase 7 (matrilysin, uterine) antibody", matrix metalloproteinase-7 antibody, uterine metalloproteinase antibody, matrin antibody, matrilysin antibody, pump-1 protease antibody, "matrix metallopeptidase 7 (matrilysin, uterine) antibody"|
|Cellular Localization||Secreted , extracellular space , extracellular matrix |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MMP7. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat, Bovine|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Sheep (85%)|