|Full Name||matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)|
|Product Description||Rabbit Polyclonal antibody to MMP9 (matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase))|
|Background||Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq]|
|Synonyms||CLG4B antibody, GELB antibody, MANDP2 antibody, MMP-9 antibody, MMP9 antibody, matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) antibody, macrophage gelatinase antibody, matrix metalloproteinase-9 antibody, 92 kDa gelatinase antibody, 92 kDa type IV collagenase antibody, type V collagenase antibody, matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) antibody|
|Cellular Localization||Secreted , extracellular space , extracellular matrix |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MMP9. The exact sequence is proprietary.|
|Species Reactivity||Human, Bovine|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog, Pig, Rabbit, Rhesus Monkey|
|Predict Reactivity Note||Mouse (82%), Rat (84%), Dog (81%), Pig (84%), Rabbit (89%), Rhesus Monkey (96%)|