|Full Name||myelin oligodendrocyte glycoprotein|
|Product Description||Rabbit polyclonal antibody to MOG (myelin oligodendrocyte glycoprotein)|
|Background||The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]|
|Synonyms||MGC26137 antibody, MOGIG2 antibody, MOG antibody, myelin-oligodendrocyte glycoprotein antibody, MOG Ig-AluB antibody, myelin oligodendrocyte glycoprotein antibody|
|Cellular Localization||Isoform 1: Cell membrane; Multi-pass membrane protein , Isoform 5: Cell membrane; Multi-pass membrane protein , Isoform 2: Cell membrane; Single-pass type I membrane protein , Isoform 3: Cell membrane; Single-pass type I membrane protein , Isoform 4: Cell|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MOG. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Human (100%)|