|Full Name||TTK protein kinase|
|Product Description||Rabbit Polyclonal antibody to MPS1|
|Background||This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]|
|Synonyms||TTK protein kinase Antibody, MPH1 Antibody, TTK Antibody, PYT Antibody, CT96 Antibody, MPS1L1 Antibody, ESK Antibody|
|Immunogen||KLH conjugated synthetic peptide derived from human MPS1|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Bovine, Rabbit, Pig, Dog|