|Full Name||major histocompatibility complex, class I-related|
|Product Description||Rabbit polyclonal antibody to MR1 (major histocompatibility complex, class I-related)|
|Background||Has antigen presentation function. Involved in the development and expansion of a small population of T cells expressing an invariant T cell receptor alpha chain called mucosal-associated invariant T cells (MAIT). MAIT cells are preferentially located in the gut lamina propria and therfore may be involed in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.|
|Synonyms||FLJ31593 antibody, HLALS antibody, MR1 antibody, MHC class-I related-gene protein antibody, MHC class I-like antigen MR-1 antibody, class I histocompatibility antigen-like protein antibody, major histocompatibility complex class I-related gene protein antibody, "major histocompatibility complex, class I-like sequence antibody", MHC class I-related gene protein antibody, "major histocompatibility complex, class I-related antibody"|
|Cellular Localization||Cell membrane; Single-pass membrane protein; Extracellular side , Endoplasmic reticulum , Isoform 4: Secreted |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MR1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Human (100%)|