|Full Name||chromosome 20 open reading frame 20|
|Product Description||Rabbit polyclonal antibody to MRGBP (chromosome 20 open reading frame 20)|
|Background||Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.|
|Synonyms||Eaf7 antibody, FLJ10914 antibody, MRG15BP antibody, MRGBP antibody, URCC4 antibody, C20orf20 antibody, MRG-binding protein antibody, MRG(MORF4-related gene)-binding protein antibody, chromosome 20 open reading frame 20 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MRGBP. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (97%), Rat (97%), Bovine (95%)|