|Full Name||mitochondrial ribosomal protein L12|
|Product Description||Rabbit Polyclonal antibody to MRPL12 (mitochondrial ribosomal protein L12)|
|Background||Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq]|
|Synonyms||5c5-2 antibody, FLJ60124 antibody, L12mt antibody, MGC8610 antibody, MRP-L31/34 antibody, MRPL7 antibody, MRPL7/L12 antibody, RPML12 antibody, MRPL12 antibody, MRP-L12 antibody, "39S ribosomal protein L12, mitochondrial antibody", mitochondrial ribosomal protein L12 antibody|
|Cellular Localization||Mitochondrion |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MRPL12. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (83%), Rhesus Monkey (94%), Bovine (86%)|