|Full Name||mitochondrial ribosomal protein L21|
|Product Description||Rabbit Polyclonal antibody to MRPL21 (mitochondrial ribosomal protein L21)|
|Background||Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD). [provided by RefSeq]|
|Synonyms||L21mt antibody, MGC62013 antibody, MRP-L21 antibody, MRPL21 antibody, "39S ribosomal protein L21, mitochondrial antibody", mitochondrial ribosomal protein L21 antibody|
|Cellular Localization||Mitochondrion |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MRPL21. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Rat (84%), Bovine (82%)|