MRPS22 antibody [N3C3]
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||41 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLaS3 , HepG2 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||mitochondrial ribosomal protein S22|
|Product Description||Rabbit Polyclonal antibody to MRPS22 (mitochondrial ribosomal protein S22)|
|Background||Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq. [provided by RefSeq]|
|Synonyms||C3orf5 antibody, COXPD5 antibody, GIBT antibody, MRP-S22 antibody, RPMS22 antibody, MRPS22 antibody, S22mt antibody, "28S ribosomal protein S22, mitochondrial antibody", mitochondrial ribosomal protein S22 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MRPS22. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (85%), Rat (85%), Bovine (86%)|