|Full Name||Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa|
|Product Description||Rabbit Polyclonal antibody to MTBP (Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa)|
|Background||Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent TP53/p53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of TP53/p53 and its subsequent degradation. |
|Synonyms||MDM2BP antibody, MTBP antibody, hMTBP antibody, mdm2-binding protein antibody, "MDM2 (mouse double minute 2)-binding protein, 104kD antibody", "Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MTBP. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Mouse (81%), Bovine (89%)|