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1 .GTX10115 MUC1 antibody [M10G4]

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MUC1 antibody [M10G4]


  • Host / ClonalityMouse Monoclonal
  • Clone NameM10G4
  • ApplicationsELISA
  • Species reactivityHuman
Cat No: GTX10115
Package Price Qty
100 μgUSD 289.00
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  • Datasheet
  • Application Information: MUC1 antibody [M10G4]

Catalog Number GTX10115
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Product Name MUC1 antibody [M10G4]
See all MUC1 products
ApplicationsELISA
Application Note
Suggested dilutionReference
ELISAAssay-dependent dilution  
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
Form SuppliedLiquid
Concentration3 mg/ml (Please refer to the vial label for the specific concentration)
PurificationProtein A purified

  • Specifications: MUC1 antibody [M10G4]

Full Namemucin 1, cell surface associated
BackgroundThis gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
SynonymsPUM Antibody , MUC1\/SEC Antibody , MUC1/ZD Antibody , H23AG Antibody , KL6 Antibody , EMA Antibody , CA\ 153 Antibody , PEMT Antibody , PEM Antibody , CD227 Antibody , MAM6 Antibody , MUC1\/X Antibody
Cellular LocalizationCell Membrane and Cytoplasmic
SpecificityRepeat of VNTR extracellular portion of MUC1 molecule. Reacts with VNTR5 and VNTR20†recombinant unglycosylated fragments of MUC1 protein and underglycosylated MUC1. Does not recognize natural MUC1 protein isolated from human milk by affinity purification on carbohydrate. Belongs to Mab cluster 1-4 according to ISOMB TD-4 classification . No cross-reactivity with egg white avidin.
HostMouse
ClonalityMonoclonal
Clone NameM10G4
IsotypeIgG
ImmunogenFull length protein (Human). A high molecular weight, more than 300 kDa, glycoprotein from human milk-fat globule molecule.
Antigen SpeciesHuman
Species ReactivityHuman
ConjugationUnconjugated

  • Storage Conditions: MUC1 antibody [M10G4]

Storage BufferPhosphate-buffered saline, pH 7.4, 0.1% sodium azide
Storage InstructionKeep as concentrated solution.Store at 4° C . DO NOT FREEZE.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Type of cancer > Breast > Other
  • Cancer > Type of cancer > Gastrointestinal > Stomach
  • Cancer > Type of cancer > Lung > Other
  • Cancer > Type of cancer > Ovarian
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MUC1 antibody [M10G4] validated data
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