|Full Name||tripartite motif containing 63|
|Product Description||Rabbit Polyclonal antibody to MURF1 (tripartite motif-containing 63)|
|Background||This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq]|
|Synonyms||FLJ32380 antibody, IRF antibody, MURF1 antibody, MURF2 antibody, RNF28 antibody, SMRZ antibody, TRIM63 antibody, iris ring finger protein antibody, muscle specific ring finger protein 2 antibody, ring finger protein 28 antibody, E3 ubiquitin-protein ligase TRIM63 antibody, striated muscle RING zinc finger protein antibody, tripartite motif-containing 63 antibody, muscle-specific RING finger protein 1 antibody, tripartite motif-containing protein 63 antibody, tripartite motif containing 63 antibody|
|Cellular Localization||Cytoplasm (By similarity) , Nucleus (By similarity) |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human MURF1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Pig, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Pig (100%), Rhesus Monkey (100%), Bovine (100%)|