MUTYH antibody [N3C3]
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||60 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , NIH-3T3|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||mutY homolog (E. coli)|
|Product Description||Rabbit polyclonal antibody to MYH (mutY homolog (E. coli))|
|Background||This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]|
|Synonyms||CYP2C antibody, MGC4416 antibody, MYH antibody, MUTYH antibody, A/G-specific adenine DNA glycosylase antibody, mutY homolog (E. coli) antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MUTYH. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|