|Full Name||mevalonate kinase|
|Product Description||Rabbit polyclonal antibody to MVK (mevalonate kinase)|
|Background||This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene. [provided by RefSeq]|
|Synonyms||FLJ96772 antibody, LRBP antibody, MK antibody, MVLK antibody, MVK antibody, mevalonate kinase 1 antibody, mevalonate kinase antibody, LH receptor mRNA-binding protein antibody|
|Cellular Localization||Cytoplasm , Peroxisome |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human MVK. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Bovine|
|Predict Reactivity Note||Mouse (86%), Rat (87%), Bovine (83%)|