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1 .GTX113601 MVP/LRP antibody

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MVP/LRP antibody

Knockout/Knockdown

  • Host / ClonalityRabbit Polyclonal
  • ApplicationsICC/IF, IHC-P, WB
  • Species reactivityHuman, Mouse
Cat No: GTX113601
Package Price Qty
25 μlUSD 119.00
100 μlUSD 319.00
Add to cart
 
  • Anti-MVP/LRP antibody used in Western Blot (WB). GTX113601
  • Anti-MVP/LRP antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX113601
  • Anti-MVP/LRP antibody used in Western Blot (WB). GTX113601
  • Anti-MVP/LRP antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX113601
  • Anti-MVP/LRP antibody used in Western Blot (WB). GTX113601
  • Anti-MVP/LRP antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX113601
  • Anti-MVP/LRP antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX113601
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  • Datasheet
  • Bio-info
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  • Application Information: MVP/LRP antibody

Catalog Number GTX113601
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Product Name MVP/LRP antibody
See all MVP/LRP products
ApplicationsICC/IF, IHC-P, WB
Application Note
Suggested dilutionReference
Immunocytochemistry/ Immunofluorescence (ICC/IF)1:100-1:1000*  
IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000*  
Western Blot (WB)1:500-1:3000*  
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
Predicted Target Size99 kDa (note) IsoForm (5)
Positive ControlsHeLa , Molt-4 , Neuro2A , GL261 , C8D30 , BCL-1 , Raw264.7
Form SuppliedLiquid
Concentration1 mg/ml (Please refer to the vial label for the specific concentration)
PurificationPurified by antigen-affinity chromatography.

  • Specifications: MVP/LRP antibody

Full Namemajor vault protein
BackgroundThis gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts. [provided by RefSeq]
SynonymsLRP antibody, VAULT1 antibody, MVP antibody, lung resistance-related protein antibody, major vault protein antibody
Cellular LocalizationCytoplasm , Nucleus , nuclear pore complex
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ImmunogenRecombinant protein encompassing a sequence within the center region of human MVP/LRP. The exact sequence is proprietary.
Antigen SpeciesHuman
Species ReactivityHuman, Mouse
Predicted Cross Reactivity species Predicted cross-reactivity:
    Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
    Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
Rat, Dog, Cat, Bovine
Predict Reactivity NoteRat (90%), Dog (91%), Cat (93%), Bovine (88%)
ConjugationUnconjugated

  • Storage Conditions: MVP/LRP antibody

Storage Buffer0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage InstructionKeep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
NotesFor In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ResearchArea
  • Cancer > Drug resistant
More Hide
MVP/LRP antibody validated data
  • Anti-MVP/LRP antibody used in Western Blot (WB). GTX113601
    • GTX113601 WB Image
      Wild-type (WT) and MVP/LRP knockout (KO) HeLa cell extracts (30 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with MVP/LRP antibody (GTX113601) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
      CRISPR knockout cell lines generated by www.edigene.com
      Top
  • Anti-MVP/LRP antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX113601
    • GTX113601 IHC-P Image
      MVP/LRP antibody detects MVP/LRP protein at cytoplasm in human breast carcinoma by immunohistochemical analysis.
      Sample: Paraffin-embedded human breast carcinoma.
      MVP/LRP antibody (GTX113601) diluted at 1:500.
      Top
  • Anti-MVP/LRP antibody used in Western Blot (WB). GTX113601
    • GTX113601 WB Image
      Sample (30 µg of whole cell lysate)
      A: Molt-4 (GTX27912)
      7.5% SDS PAGE
      GTX113601 diluted at 1:1000
      The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
      Top
  • Anti-MVP/LRP antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX113601
    • GTX113601 ICC/IF Image
      Immunofluorescence analysis of paraformaldehyde-fixed A431, using MVP/LRP(GTX113601) antibody at 1:200 dilution.
      Top
  • Anti-MVP/LRP antibody used in Western Blot (WB). GTX113601
    • GTX113601 WB Image
      MVP/LRP antibody detects MVP protein by western blot analysis.
      A. 30 µg Neuro2A whole cell lysate/extract
      B. 30 µg GL261 whole cell lysate/extract
      C. 30 µg C8D30 whole cell lysate/extract
      D. 30 µg BCL-1 whole cell lysate/extract
      E. 30 µg Raw264.7 whole cell lysate/extract
      7.5% SDS-PAGE
      MVP/LRP antibody (GTX113601) dilution: 1:1000
      The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
      Top
  • Anti-MVP/LRP antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX113601
    • GTX113601 IHC-P Image
      Immunohistochemical analysis of paraffin-embedded A549 xenograft, using LRP(MVP)(GTX113601) antibody at 1:500 dilution.
      Top
  • Anti-MVP/LRP antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX113601
    • GTX113601 IHC-P Image
      MVP/LRP antibody detects MVP/LRP protein at cytosol on mouse colon by immunohistochemical analysis.
      Sample: Paraffin-embedded mouse colon.
      MVP/LRP antibody (GTX113601) dilution: 1:500.
      Top
  • Anti-MVP/LRP antibody used in Western Blot (WB). GTX113601
    • GTX113601 WB Image
      Wild-type (WT) and MVP/LRP knockout (KO) HeLa cell extracts (30 µg) were separated by 7.5% SDS-PAGE, and the membrane was blotted with MVP/LRP antibody (GTX113601) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
      CRISPR knockout cell lines generated by www.edigene.com
      Top
  • Anti-MVP/LRP antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX113601
    • GTX113601 IHC-P Image
      MVP/LRP antibody detects MVP/LRP protein at cytoplasm in human breast carcinoma by immunohistochemical analysis.
      Sample: Paraffin-embedded human breast carcinoma.
      MVP/LRP antibody (GTX113601) diluted at 1:500.
      Top
  • Anti-MVP/LRP antibody used in Western Blot (WB). GTX113601
    • GTX113601 WB Image
      Sample (30 µg of whole cell lysate)
      A: Molt-4 (GTX27912)
      7.5% SDS PAGE
      GTX113601 diluted at 1:1000
      The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
      Top
  • Anti-MVP/LRP antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX113601
    • GTX113601 ICC/IF Image
      Immunofluorescence analysis of paraformaldehyde-fixed A431, using MVP/LRP(GTX113601) antibody at 1:200 dilution.
      Top
  • Anti-MVP/LRP antibody used in Western Blot (WB). GTX113601
    • GTX113601 WB Image
      MVP/LRP antibody detects MVP protein by western blot analysis.
      A. 30 µg Neuro2A whole cell lysate/extract
      B. 30 µg GL261 whole cell lysate/extract
      C. 30 µg C8D30 whole cell lysate/extract
      D. 30 µg BCL-1 whole cell lysate/extract
      E. 30 µg Raw264.7 whole cell lysate/extract
      7.5% SDS-PAGE
      MVP/LRP antibody (GTX113601) dilution: 1:1000
      The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
      Top
  • Anti-MVP/LRP antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX113601
    • GTX113601 IHC-P Image
      Immunohistochemical analysis of paraffin-embedded A549 xenograft, using LRP(MVP)(GTX113601) antibody at 1:500 dilution.
      Top
  • Anti-MVP/LRP antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX113601
    • GTX113601 IHC-P Image
      MVP/LRP antibody detects MVP/LRP protein at cytosol on mouse colon by immunohistochemical analysis.
      Sample: Paraffin-embedded mouse colon.
      MVP/LRP antibody (GTX113601) dilution: 1:500.
      Top
Back to Top
Target Bioinfo/ Predicted Isoform Cross Reactivity
SpeciesGene nameGene IDSwissProtOMIMIsoform (mRNA)Protein Accession#MW
Homo sapiensMVP9961Q14764605088NP_00128013392.57
Homo sapiensMVP9961Q14764605088NP_00128013491.99
Homo sapiensMVP9961Q14764605088BC015623AAH1562399.35
Homo sapiensMVP9961Q14764605088NM_005115NP_00510699.35
Homo sapiensMVP9961Q14764605088NM_017458NP_05944799.35

Cross-react Bioinfo
SpeciesGene nameGene IDSwissProtIsoform (mRNA)Protein Accession#MW
Rattus norvegicusMvp64681Q62667NM_022715NP_07320695.82
Mus musculusMvp78388Q9EQK5NM_080638NP_54236996.88
    *MSDS
    MSDS-Glycerol.pdf
    MSDS-Thimerosal.pdf
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