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Catalog Number
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GTX113601
(
0
)
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Product Name
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MVP/LRP antibody
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| Applications | ICC/IF, IHC-P, WB |
| Application Note |
| Suggested dilution | Reference |
| Immunocytochemistry/ Immunofluorescence (ICC/IF) | 1:100-1:1000* |
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| IHC (Formalin-fixed paraffin-embedded sections) | 1:100-1:1000* |
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| Western Blot (WB) | 1:500-1:3000* |
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Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
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| Predicted Target Size | 99 kDa (note)
 (5)
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| Positive Controls | HeLa , Molt-4 , Neuro2A , GL261 , C8D30 , BCL-1 , Raw264.7 |
| Form Supplied | Liquid |
| Concentration | 1
mg/ml
(Please refer to the vial label for the specific concentration) |
| Purification | Purified by antigen-affinity chromatography. |
| Full Name | major vault protein |
| Product Description | Rabbit Polyclonal antibody to MVP/LRP (major vault protein) |
| Background | This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts. [provided by RefSeq] |
| Synonyms | LRP antibody, VAULT1 antibody, MVP antibody, lung resistance-related protein antibody, major vault protein antibody |
| Cellular Localization | Cytoplasm , Nucleus , nuclear pore complex |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human MVP/LRP. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human, Mouse |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Rat, Dog, Cat, Bovine |
| Predict Reactivity Note | Rat (90%), Dog (91%), Cat (93%), Bovine (88%) |
| Conjugation | Unconjugated |