|Full Name||Myb-like, SWIRM and MPN domains 1|
|Product Description||Rabbit Polyclonal antibody to MYSM1 (Myb-like, SWIRM and MPN domains 1)|
|Background||Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. |
|Synonyms||Myb-like, SWIRM and MPN domains 1 Antibody, 2ADUB Antibody, 2A-DUB Antibody, RP4-592A1.1 Antibody|
|Cellular Localization||Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human MYSM1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Chicken, Bovine|
|Predict Reactivity Note||Mouse (86%), Chicken (81%), Bovine (90%)|