|Full Name||melatonin receptor 1A|
|Product Description||Rabbit Polyclonal antibody to Melatonin Receptor 1A (melatonin receptor type 1A)|
|Background||This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq]|
|Synonyms||MEL-1A-R antibody, MT1 antibody, MTNR1A antibody, melatonin receptor type 1A antibody, mel1a receptor antibody, melatonin receptor 1A antibody|
|Cellular Localization||Cell membrane; Multi-pass membrane protein |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human Melatonin Receptor 1A. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Chicken, Sheep|
|Predict Reactivity Note||Mouse (90%), Rat (88%), Chicken (84%), Sheep (85%)|