MyD88 antibody, Internal
|Applications||ELISA, IHC, IHC-P, WB|
|Application Note||Approx 33kDa band observed in HumanThymus lysates (calculated MW of 33.2kDa according to NP_002459.1). Recommended concentration: 0.03-0.1µg/ml. In paraffin embedded tonsil, stains clusters of cells some of which are likely to be plasma cells. In the interfollicular area occasional strongly stained areas. Epithelium is weakly positive. Recommended concentration, 2-5µg/ml. Data obtained from previous batch. |
|Positive Controls||The peptide used to product this antibody is available for purchase (Catalog Number:GTX89605-PEP).|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.|
|Full Name||myeloid differentiation primary response gene (88)|
|Product Description||Goat polyclonal antibody to MYD88|
|Background||Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. |
|Synonyms||myeloid differentiation primary response gene (88), MYD88, MYD88D, myeloid differentiation primary response gene88, myeloid differentiation primary response gene 88|
|Specificity||This antibody is specific for MYD88.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Dog|