|Applications||ICC/IF, IHC-Fr, IHC-P, WB|
Not tested in other applications.
|IHC (Frozen sections)||1:100-1:1000*
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||100 kDa (note)
|Positive Controls||HeLa , HepG2 , Mouse brain , Rat brain , *A549|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||cadherin 2, type 1, N-cadherin (neuronal)|
|Product Description||Rabbit Polyclonal antibody to N-Cadherin (cadherin 2, type 1, N-cadherin (neuronal))|
|Background||This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq]|
|Synonyms||neural-cadherin antibody, neural cadherin antibody, calcium-dependent adhesion protein, neuronal antibody, cadherin-2 antibody, cadherin 2, type 1, N-cadherin (neuronal) antibody, cadherin 2, N-cadherin (neuronal) antibody, NCAD antibody, N-cadherin 1 antibody, CDw325 antibody, CDHN antibody, CDH2 antibody, CD325 antibody|
|Cellular Localization||Cell membrane |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human N-Cadherin. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Dog, Chicken, Bovine|
|Predict Reactivity Note||Dog (100%), Chicken (100%), Bovine (100%)|