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Catalog Number
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GTX112734
(
4
)
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Product Name
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N-Cadherin antibody [N1N3]
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| Applications | ICC/IF, IHC-P, WB |
| Application Note |
| Suggested dilution | Reference |
| Immunocytochemistry/ Immunofluorescence (ICC/IF) | 1:100-1:1000* |
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| IHC (Formalin-fixed paraffin-embedded sections) | 1:100-1:1000* |
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| Western Blot (WB) | 1:500-1:3000* |
Y |
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
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| Predicted Target Size | 100 kDa (note)
 (2)
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| Positive Controls | NT2D1 , U87-MG , SK-N-SH , IMR-32 , SK-N-AS , mouse brain , rat brain , PC-12 , Rat2 |
| Form Supplied | Liquid |
| Concentration | 1
mg/ml
(Please refer to the vial label for the specific concentration) |
| Purification | Purified by antigen-affinity chromatography. |
| Full Name | cadherin 2, type 1, N-cadherin (neuronal) |
| Background | This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq] |
| Synonyms | neural-cadherin antibody, neural cadherin antibody, calcium-dependent adhesion protein, neuronal antibody, cadherin-2 antibody, cadherin 2, type 1, N-cadherin (neuronal) antibody, cadherin 2, N-cadherin (neuronal) antibody, NCAD antibody, N-cadherin 1 antibody, CDw325 antibody, CDHN antibody, CDH2 antibody, CD325 antibody |
| Cellular Localization | Cell membrane |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human N-Cadherin. The exact sequence is proprietary. |
| Antigen Species | Human |
| Species Reactivity | Human, Mouse, Rat |
Predicted Cross Reactivity species  Predicted cross-reactivity:
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
| Xenopus laevis, Dog, Chicken, Bovine |
| Predict Reactivity Note | Xenopus laevis (82%), Dog (96%), Chicken (90%), Bovine (96%) |
| Conjugation | Unconjugated |