|Full Name||NGFI-A binding protein 2 (EGR1 binding protein 2)|
|Product Description||Rabbit Polyclonal antibody to NAB2 (NGFI-A binding protein 2 (EGR1 binding protein 2))|
|Background||This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]|
|Synonyms||MADER antibody, MGC75085 antibody, NAB2 antibody, EGR1 binding protein 2 antibody, melanoma-associated delayed early response protein antibody, EGR-1-binding protein 2 antibody, NGFI-A-binding protein 2 antibody, NGFI-A binding protein 2 (EGR1 binding protein 2) antibody|
|Cellular Localization||Nucleus (By similarity) |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human NAB2. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (98%), Rhesus Monkey (100%), Bovine (99%)|