NAK antibody [N2C1], Internal
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||84 kDa (note)
|Positive Controls||HeLa , HepG2 , NT2D1 , mouse testis|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||TANK-binding kinase 1|
|Product Description||Rabbit Polyclonal antibody to NAK (TANK-binding kinase 1)|
|Background||The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK. [provided by RefSeq]|
|Synonyms||FLJ11330 antibody, NAK antibody, T2K antibody, TBK1 antibody, NF-kB-activating kinase antibody, serine/threonine-protein kinase TBK1 antibody, NF-kappa-B-activating kinase antibody, TANK-binding kinase 1 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human NAK. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Pig, Chicken, Rhesus Monkey, Bovine|
|Predict Reactivity Note||Rat (93%), Pig (98%), Chicken (89%), Rhesus Monkey (98%), Bovine (96%)|