|Full Name||N-acetylneuraminic acid synthase|
|Product Description||Rabbit Polyclonal antibody to NANS (N-acetylneuraminic acid synthase)|
|Background||This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant. [provided by RefSeq]|
|Synonyms||SAS antibody, NANS antibody, sialic acid synthase antibody, N-acetylneuraminate synthase antibody, N-acetylneuraminic acid phosphate synthase antibody, N-acetylneuraminate-9-phosphate synthase antibody, sialic acid phosphate synthase antibody, N-acetylneuraminic acid synthase antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human NANS. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Xenopus laevis, Pig, Chicken, Bovine|
|Predict Reactivity Note||Mouse (97%), Rat (97%), Xenopus laevis (84%), Pig (98%), Chicken (93%), Bovine (97%)|