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Nav1.7 antibody

Anti-Nav1.7 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54800
Anti-Nav1.7 antibody used in IHC (Frozen sections) (IHC-Fr). GTX54800
Anti-Nav1.7 antibody used in Western Blot (WB). GTX54800
Anti-Nav1.7 antibody used in Western Blot (WB). GTX54800

Cat. No. GTX54800

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-Fr

Reactivity

Human, Mouse, Rat
Package
50 μl ($639)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

226 kDa. ( Note )

Predict Reactivity

Rabbit(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.8 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Peptide (C)EFTSIGRSR IMGLSE, corresponding to amino acid residues 446-460 (Intracellular loop between domains I and II) of rat NaV1.7 (Accession  : O08562).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

sodium voltage-gated channel alpha subunit 9 , Nav1.7 , PN1 , Scn2a

Cellular Localization

Cell membrane

Background

voltage-dependent sodium channel alpha subunit which may be the major channel in the peripheral nervous system [RGD, Feb 2006]

Database

Research Area

DATA IMAGES

Anti-Nav1.7 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54800

GTX54800 ICC/IF Image

ICC/IF analysis of PFA-fixed rat DRG primary cells using GTX54800 Nav1.7 antibody.
Dilution : 1:200

Anti-Nav1.7 antibody used in IHC (Frozen sections) (IHC-Fr). GTX54800

GTX54800 IHC-Fr Image

IHC-Fr analysis of rat DRG tissue using GTX54800 Nav1.7 antibody.
Panel A : NaV1.7 channel (red) in DRG neurons.
Panel B : Staining with mouse anti-Parvalbumin (green) in the same DRG section. 
Panel C : Merge of NaV1.7 and Parvalbumin demonstrates colocalization (arrows).

Anti-Nav1.7 antibody used in Western Blot (WB). GTX54800

GTX54800 WB Image

WB analysis of DRG lysates using GTX54800 Nav1.7 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

Anti-Nav1.7 antibody used in Western Blot (WB). GTX54800

GTX54800 WB Image

WB analysis of ND7/23 cell (lanes 1,3) and rat brain membranes (lanes 2,4) lysates using GTX54800 Nav1.7 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 639