NCOA62 antibody [N3C3]
|Applications||ICC/IF, IHC-P, WB|
Not tested in other applications.
|IHC (Formalin-fixed paraffin-embedded sections)||1:100-1:1000*
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||61 kDa (note)
|Positive Controls||A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse liver|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||SNW domain containing 1|
|Product Description||Rabbit Polyclonal antibody to NCOA62 (SNW domain containing 1)|
|Background||This gene, a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. [provided by RefSeq]|
|Synonyms||Bx42 antibody, MGC119379 antibody, NCOA-62 antibody, PRPF45 antibody, Prp45 antibody, SKIIP antibody, SKIP antibody, SNW1 antibody, SKI-interacting protein antibody, nuclear receptor coactivator NCoA-62 antibody, SKI interacting protein antibody, "nuclear receptor coactivator, 62-kD antibody", SNW domain-containing protein 1 antibody, homolog of Drosophila BX42 antibody, nuclear protein SkiP antibody, SNW domain containing 1 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human NCOA62. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Zebrafish, Xenopus laevis, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (98%), Zebrafish (80%), Xenopus laevis (83%), Chimpanzee (99%), Bovine (99%)|