|Full Name||nuclear receptor corepressor 1|
|Product Description||Rabbit Polyclonal antibody to NCOR1 (nuclear receptor corepressor 1)|
|Background||This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined. [provided by RefSeq]|
|Synonyms||TRAC1 Antibody , N-CoR Antibody , hN-CoR Antibody , nuclear receptor corepressor 1 Antibody , N-CoR1 Antibody|
|Cellular Localization||Nucleus |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NCOR1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Bovine (100%)|