|Full Name||NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa|
|Product Description||Rabbit Polyclonal antibody to NDUFA5 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa)|
|Background||The human NDUFA5 gene codes for the B13 subunit of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. The high degree of conservation of NDUFA5 extending to plants and fungi indicates its functional significance in the enzyme complex. The protein localizes to the inner mitochondrial membrane as part of the 7 component-containing, water soluble "iron-sulfur protein" (IP) fraction of complex I, although its specific role is unknown. It is assumed to undergo post-translational removal of the initiator methionine and N-acetylation of the next amino acid. The predicted secondary structure is primarily alpha helix, but the carboxy-terminal half of the protein has high potential to adopt a coiled-coil form. The amino-terminal part contains a putative beta sheet rich in hydrophobic amino acids that may serve as mitochondrial import signal. Related pseudogenes have also been identified on four other chromosomes. [provided by RefSeq]|
|Synonyms||B13 antibody, CI-13KD-B antibody, CI-13kB antibody, DKFZp781K1356 antibody, FLJ12147 antibody, NUFM antibody, UQOR13 antibody, NDUFA5 antibody, type I dehydrogenase antibody, NADH-ubiquinone oxidoreductase 13 kDa-B subunit antibody, Complex I-13KD-B antibody, ubiquinone reductase antibody, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 antibody, complex I subunit B13 antibody, complex I 13kDa subunit B antibody, "NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa antibody"|
|Cellular Localization||Mitochondrion inner membrane; Peripheral membrane protein; Matrix side |
|Immunogen||Full length human NDUFA5 Recombinant protein.|
|Species Reactivity||Human, Mouse|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rat, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Rat (80%), Rhesus Monkey (94%), Chimpanzee (100%), Bovine (87%)|