|Full Name||NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)|
|Product Description||Rabbit Polyclonal antibody to NDUFS1 (NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase))|
|Background||The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. [provided by RefSeq]|
|Synonyms||CI-75Kd antibody, CI-75k antibody, MGC26839 antibody, PRO1304 antibody, NDUFS1 antibody, "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial antibody", mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit antibody, complex I 75kDa subunit antibody, "complex I, mitochondrial respiratory chain, 75-kD subunit antibody", "NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) antibody"|
|Cellular Localization||Mitochondrion inner membrane |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human NDUFS1. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Chicken, Chimpanzee, Bovine|
|Predict Reactivity Note||Zebrafish (82%), Xenopus laevis (85%), Chicken (86%), Chimpanzee (100%), Bovine (96%)|