|Full Name||NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)|
|Product Description||Rabbit Polyclonal antibody to NDUFS4 (NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase))|
|Background||This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes. [provided by RefSeq]|
|Synonyms||AQDQ antibody, CI-18 antibody, NDUFS4 antibody, CI-AQDQ antibody, CI-18 kDa antibody, "NADH-coenzyme Q reductase, 18-KD antibody", mitochondrial respiratory chain complex I (18-KD subunit) antibody, complex I 18kDa subunit antibody, complex I-AQDQ antibody, NADH dehydrogenase (ubiquinone) iron-sulfur protein 4 antibody, complex I-18 kDa antibody, "NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial antibody", NADH-ubiquinone oxidoreductase 18 kDa subunit antibody, "NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) antibody"|
|Cellular Localization||Mitochondrion inner membrane; Peripheral membrane protein; Matrix side |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human NDUFS4. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Chimpanzee, Bovine|
|Predict Reactivity Note||Zebrafish (80%), Chimpanzee (99%), Bovine (89%)|