|Full Name||neurofilament, heavy polypeptide|
|Product Description||Rabbit polyclonal antibody to 200 kD Neurofilament Heavy (neurofilament, heavy polypeptide 200kDa)|
|Background||Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq]|
|Synonyms||NFH antibody, NEFH antibody, NF-H antibody, neurofilament heavy polypeptide antibody, "neurofilament, heavy polypeptide 200kDa antibody", 200 kDa neurofilament protein antibody, neurofilament triplet H protein antibody, "neurofilament, heavy polypeptide antibody"|
|Target||200 kD Neurofilament Heavy |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human NF-H. The exact sequence is proprietary.|
|Species Reactivity||Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Human (100%), Dog (89%)|