|Full Name||nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1|
|Product Description||Rabbit Polyclonal antibody to NFAT2 (nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1)|
|Background||The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq]|
|Synonyms||MGC138448 antibody, NF-ATC antibody, NFAT2 antibody, NFATc antibody, NFATC1 antibody, nuclear factor of activated T-cells, cytoplasmic 1 antibody, NFAT transcription complex cytosolic component antibody, NF-ATc1 antibody, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 antibody|
|Cellular Localization||Cytoplasm , Nucleus |
|Immunogen||Recombinant protein encompassing a sequence within the center region of human NFAT2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat|
|Predict Reactivity Note||Human (100%), Mouse (84%), Rat (85%)|