|Full Name||nuclear transcription factor, X-box binding 1|
|Product Description||Rabbit polyclonal antibody to NFX1 (nuclear transcription factor, X-box binding 1)|
|Background||MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified. [provided by RefSeq]|
|Synonyms||DKFZp779G2416 antibody, MGC20369 antibody, NFX2 antibody, NFX1 antibody, "nuclear transcription factor, X box-binding protein 1 antibody", transcriptional repressor NF-X1 antibody, "nuclear transcription factor, X-box binding 1 antibody"|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human NFX1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Bovine|
|Predict Reactivity Note||Human (100%), Mouse (95%), Rat (96%), Bovine (92%)|