|Full Name||killer cell lectin-like receptor subfamily C, member 2|
|Product Description||Rabbit Polyclonal antibody to NKG2-C (killer cell lectin-like receptor subfamily C, member 2)|
|Background||Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. [provided by RefSeq]|
|Synonyms||CD159c antibody, MGC138244 antibody, NKG2-C antibody, NKG2C antibody, KLRC2 antibody, NK cell receptor C antibody, NKG2-C type II integral membrane protein antibody, CD159 antigen-like family member C antibody, NKG2-C-activating NK receptor antibody, "killer cell lectin-like receptor subfamily C, member 2 antibody"|
|Cellular Localization||Membrane; Single-pass type II membrane protein |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human NKG2-C. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Rhesus Monkey, Chimpanzee|
|Predict Reactivity Note||Rhesus Monkey (100%), Chimpanzee (100%)|