|Full Name||killer cell lectin-like receptor subfamily K, member 1|
|Product Description||Rabbit Polyclonal antibody to NKG2D (killer cell lectin-like receptor subfamily K, member 1)|
|Background||Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. [provided by RefSeq]|
|Synonyms||CD314 antibody, D12S2489E antibody, FLJ17759 antibody, FLJ75772 antibody, KLR antibody, NKG2-D antibody, NKG2D antibody, KLRK1 antibody, NK cell receptor D antibody, NKG2-D-activating NK receptor antibody, NKG2-D type II integral membrane protein antibody, killer cell lectin-like receptor subfamily K, member 1 antibody|
|Cellular Localization||Membrane; Single-pass type II membrane protein |
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human NKG2D. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Predict Reactivity Note||Chimpanzee (100%)|