|Full Name||NFKB inhibitor interacting Ras-like 1|
|Product Description||Rabbit polyclonal antibody to NKIRAS1 (NFKB inhibitor interacting Ras-like 1)|
|Background||Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.|
|Synonyms||KBRAS1 antibody, kappaB-Ras1 antibody, NKIRAS1 antibody, I-kappa-B-interacting Ras-like protein 1 antibody, NF-kappa-B inhibitor-interacting Ras-like protein 1 antibody, kappa B-Ras protein 1 antibody, NFKB inhibitor interacting Ras-like protein 1 antibody, kappa B-ras 1 antibody, NFKB inhibitor interacting Ras-like 1 antibody|
|Immunogen||Recombinant protein encompassing a sequence within the center region of human kappaB-Ras1. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Human, Mouse, Rat, Rhesus Monkey, Chimpanzee|
|Predict Reactivity Note||Human (100%), Mouse (95%), Rat (95%), Rhesus Monkey (100%), Chimpanzee (100%)|