NKIRAS2 antibody [C2C3], C-term
Not tested in other applications.
*Optimal dilutions/concentrations should be determined by the researcher.
|Predicted Target Size||22 kDa (note)
|Positive Controls||293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji|
(Please refer to the vial label for the specific concentration)|
|Purification||Purified by antigen-affinity chromatography.|
|Full Name||NFKB inhibitor interacting Ras-like 2|
|Product Description||Rabbit Polyclonal antibody to NKIRAS2 (NFKB inhibitor interacting Ras-like 2)|
|Background||Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.|
|Synonyms||DKFZp434N1526 antibody, KBRAS2 antibody, MGC74742 antibody, kappaB-Ras2 antibody, NKIRAS2 antibody, NFKB inhibitor interacting Ras-like protein 2 antibody, NF-kappa-B inhibitor-interacting Ras-like protein 2 antibody, I-kappa-B-interacting Ras-like protein 2 antibody, kappa B-Ras protein 2 antibody, NFKB inhibitor interacting Ras-like 2 antibody|
|Immunogen||Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NKIRAS2. The exact sequence is proprietary.|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Mouse, Rat, Rhesus Monkey, Chimpanzee, Bovine|
|Predict Reactivity Note||Mouse (100%), Rat (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)|