|Full Name||nicotinamide nucleotide transhydrogenase|
|Product Description||Rabbit Polyclonal antibody to NNT (nicotinamide nucleotide transhydrogenase)|
|Background||This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq]|
|Synonyms||MGC126502 antibody, MGC126503 antibody, NNT antibody, pyridine nucleotide transhydrogenase antibody, NAD(P) transhydrogenase, mitochondrial antibody, nicotinamide nucleotide transhydrogenase antibody|
|Cellular Localization||Mitochondrion inner membrane; Multi-pass membrane protein; Matrix side |
|Immunogen||Recombinant protein encompassing a sequence within the C-terminus region of human NNT. The exact sequence is proprietary.|
|Species Reactivity||Human, Mouse, Rat|
|Predicted Cross Reactivity species Predicted cross-reactivity:|
Predicted cross-reactivity is based on sequence homology, with greater than 80% immunogen sequence identity considered positive.
Please note that we are only able to guarantee products to work in applications and species in which they have been tested.
|Zebrafish, Xenopus laevis, Bovine|
|Predict Reactivity Note||Zebrafish (88%), Xenopus laevis (93%), Bovine (99%)|